Lipid-lowering medications

Lipid-lowering medications

ClassGenericBrandCommon doseRenal adjust
StatinAtorvastatinLipitor10–80 mg dailyNo
StatinSimvastatinZocor10–40 mg at nightYes: caution if eGFR < 30
StatinRosuvastatinCrestor10–40 mg dailyYes: start at 5 mg if eGFR < 30
FibrateFenofibrateLipanthyl145–160 mg OD (100 mg caps also available)Yes: reduce/avoid if eGFR < 30; caution combined with statin
Cholesterol absorption inhibitorEzetimibeEzetrol10 mg dailyNo
PCSK9 inhibitorEvolocumabRepatha140 mg SC every 2 weeks or 420 mg SC once monthlyNo
PCSK9 inhibitorAlirocumabPraluent75–150 mg SC every 2 weeks (or 300 mg every 4 weeks)No
CombinationAtorvastatin + ezetimibeAtozete.g., 40/10 mg dailyNo

Educational reference for clinicians. Doses are typical adult starting points — cross-check current local policy, the formulary, and renal/hepatic function before prescribing. Last reviewed: July 2026.

Last reviewed · July 2026

MOC