Labetalol; nifedipine MR. Methyldopa is an alternative
ACEi, ARB, MRA contraindicated
AF rate control
BB or non-DHP CCB (diltiazem, verapamil) where appropriate
Avoid non-DHP CCBs in HFrEF
Antihypertensives
Class
Medication (Brand)
Dose
ACE inhibitor
Lisinopril (Zestril)
5–20 mg OD
Ramipril (Tritace)
1.25–10 mg OD
Perindopril (Coversyl)
2–8 mg OD
Captopril (Capoten)
12.5–50 mg BD or TDS
ARB
Valsartan (Diovan)
80–160 mg OD
Telmisartan (Micardis)
20–80 mg OD
Candesartan (Atacand)
8–32 mg OD
CCB (DHP)
Amlodipine (Norvasc, Istin)
5–10 mg OD
Nifedipine LA (Adalat LA)
30–60 mg OD
Lercanidipine (Lercadip)
5–20 mg OD
Thiazide-like diuretic
Indapamide (Natrilix)
1.25–2.5 mg OD
Loop diuretic
Furosemide (Lasix)
HTN/oedema: 20–80 mg PO / IV
Aldosterone antagonist
Spironolactone (Aldactone)
25–100 mg OD
Beta blockers (also anti-anginal / rate control)
Bisoprolol (Concor)
2.5–5 mg OD
Metoprolol (Lopressor)
50–100 mg BD
Carvedilol (Dilatrend)
6.25–25 mg BD
Atenolol (Tenormin)
25–100 mg OD–BD
Labetalol (Trandate)
100–400 mg BD
Central acting agent
Methyldopa (Aldomet)
250–500 mg BD / TDS
Direct vasodilator
Hydralazine (Apresoline)
100–200 mg/day in 3–4 divided doses
Combination
Amlodipine + Valsartan (Exforge)
5/160, 10/160 mg OD
Combination
Exforge HCT (+ Hydrochlorothiazide)
5/160/12.5, 10/160/12.5 mg OD
Combination
Amlodipine + Telmisartan (Twynsta)
40/5, 80/5, 80/10 mg OD
Combination
Amlodipine + Perindopril (Coveram)
5/5, 5/10, 10/10 mg OD
Combination
Telmisartan + HCTZ (Micardis Plus)
80/12.5 mg OD
Combination
Valsartan + HCTZ (Co-Diovan)
80/12.5, 160/25 mg OD
Anti-anginal
Class
Medication (Brand)
Dose
Notes
Long-acting nitrate
Isosorbide mononitrate (Monorem, Imdur)
30–60 mg OD
Keep a nitrate-free interval; headache
Short-acting nitrate
GTN (glyceryl trinitrate)
SL 0.4–0.5 mg PRN; IV infusion for ACS / pulmonary oedema
Avoid if hypotensive or recent PDE5 inhibitor
Metabolic
Trimetazidine (Vastarel MR)
35 mg BD
Add-on
Metabolic
Ranolazine (Ranexa)
375–750 mg BD
QT prolongation
If-channel inhibitor
Ivabradine (Procoralan)
5–7.5 mg BD
Sinus rhythm, HR ≥ 70
K-channel activator
Nicorandil
10–20 mg BD
Confirm local availability
First-line anti-anginals are beta blockers and CCBs (see above); agents here are add-on or alternatives.
Anti-arrhythmic
Drug (Brand)
Dose
Use / notes
Amiodarone (Cordarone)
Arrest: 300 mg IV bolus. Stable VT or AF: 150 mg IV over 10 min, repeat if it recurs, then 1 mg/min for 6 h and 0.5 mg/min for 18 h; PO load 200 mg TDS then taper
Broad (AF, VT); thyroid / lung / LFT monitoring; central line for infusion
Adenosine (Adenocor)
6 mg rapid IV push with an immediate flush → 12 mg; not terminating → cardiology
SVT; transient; warn of flushing and chest tightness; rhythm strip running
Digoxin (Lanoxin)
Load 500 mcg, then 250 mcg to ~1 mg / 24 h; maintenance 62.5–250 mcg OD
Rate control in AF; renal dose, check levels
Verapamil (Isoptin)
IV 5–10 mg slow; PO 40–120 mg TDS
Rate control; avoid in HFrEF and with IV beta blocker
Flecainide (Tambocor)
50–150 mg BD (or IV)
AF cardioversion; only if structurally normal heart
Educational reference for clinicians. Doses are typical adult starting points. Cross-check allergies, interactions, current local policy, the formulary, and renal/hepatic function before prescribing.