Blood Pressure – Hypotension

ABCs
  • Manually recheck BP and compare with baseline
  • MAP goal > 65 mmHg SBP goal > 90 mmHg
  • Look for signs of end-organ hypoperfusion
  • Volume status: JVP, skin turgor, lung exam (rales) and peripheral edema
  • Look for signs of shock type and tailor workup accordingly
causes
TypeKey Clues
SepticFever/chills, URTI, SOB, abdominal pain, diarrhea, dysuria, travel, sick contacts
HypovolemicVomiting, diarrhea, ↓ PO intake, diuretics or new antihypertensives
ObstructivePleuritic CP, hemoptysis, leg swelling, recent surgery or immobility (PE)
CardiogenicChest pain, dyspnea, palpitations, diaphoresis, syncope
OtherAnaphylaxis, neurogenic shock (e.g., spinal injury)
initial management
  • If hypoglycemicD50% 50 mL IV bolus
  • Start IV fluids
    • Normal Saline or Ringer’s Lactate 500 mL bolus
    • Repeat as needed, but monitor for fluid overload (esp. in elderly, CKD, HF)
  • Review or hold antihypertensives/sedatives
  • If persistent hypotension, start vasopressors:
    • Norepinephrine/Levophed: up to 0.4 mcg/kg/min
    • Vasopressin: up to 0.04 unit/min
  • Reassess perfusion frequently (mental status, UOP, skin)
  • Escalate early: Call senior/ICU for unstable patients
  • Central line tip: Check coagulation profile before insertion
Type of ShockKey Clues & Steps
SepticCBC, CRP, PCT, LFT/RFT, lactic acid, cultures, VBG. Start broad-spectrum antibiotics. Inotrope: norepinephrine.
HemorrhagicCBC, coag profile, reserve blood products. Transfuse PRBCs as needed.
CardiogenicECG, hs-Trop, BNP, CXR, bedside echo. Refer to cardiology.
NeurogenicCT/MRI brain & spine. Neurology consult.
Massive PEHigh suspicion → bedside echo, urgent CCU transfer, consider thrombolysis.
AnaphylaxisOxygen + epinephrine 0.3–0.5 mg IM, antihistamines, corticosteroids.

Studying for R1? The IM Rapid Review covers this in the same format — see the sample chapter.

Last reviewed · May 2026

MOC