Post-Resuscitation Care (Adult ALS)

Post-ROSC · adult ALS

Post-Resuscitation Care

The first 24 hours after ROSC — stabilize, identify the cause, and prevent re-arrest.

stabilize examine investigate monitor communicate

Step 1

Immediate priorities

  • Stabilize circulation & prevent re-arrest
  • Identify and treat reversible causes
  • Temperature control
    • Aggressive cooling to 33 °C is no longer routinely recommended
    • Maintain core temperature ≤ 37.5 °C
    • Use antipyretics and surface cooling if needed
    • Monitor temperature closely during the first 72 hours
  • History: obtain from staff, witnesses, or medical notes
  • Key reversible causes to consider
    • Myocardial infarction
    • Hypoxia, hypoglycemia
    • Stroke, overdose, electrolyte imbalance
    • Trauma, pulmonary embolism, sepsis
  • Documentation
    • Duration of arrest
    • Timeline of interventions and drug doses
Step 2

Initial stabilization

Circulation

  • Establish rapid IV / IO access
  • Give 1–2 L isotonic crystalloids if preload responsive
    • Avoid excess fluids in CHF / pulmonary edema
  • Initiate vasopressors early if hypotensive
    • Norepinephrine is first-line

If recurrent VT / VF

  • Follow ACLS algorithm
  • Consider amiodarone or lidocaine
  • Escalate to ECMO or PCI if refractory

Airway & breathing

  • If intubating, use reduced sedation doses
  • Avoid hyperventilation
    • Target SpO₂ > 94 %, PaCO₂ 40–50 mmHg
Step 3

Clinical examination

  • Confirm bilateral ventilation
  • Check for rib fractures
  • Assess for new murmurs, JVP
  • Rule out aneurysm, peritonitis
  • Perform baseline neuro exam
  • Assess brainstem reflexes: pupils, corneal, gag & cough
  • Asymmetry may suggest a stroke or structural lesion
  • Avoid early prognostication — findings may improve

Tubes & lines

  • Convert emergency lines to a central line (sterile)
  • Insert urinary catheter
  • Consider NG tube if unconscious
Step 4

Immediate investigations

  • ECG: STEMI, arrhythmias, QTc, signs of PE
  • ABG: mixed acidosis is common
    • May improve with oxygen and perfusion
    • Consider bicarbonate if severe
  • CXR: confirm ETT placement +/− NGT & rule out pneumothorax
  • Labs
    • CBC, coagulation, troponin, electrolytes & lactate
    • Repeat Q6H early on
  • Toxicology screen if relevant
  • Bedside Echo to assess regional wall-motion abnormalities
  • CT head to rule out central causes
Step 5

Monitoring

  • Continuous cardiac monitoring
  • Head of bed at 30°
  • Maintain glucose 7.8–10 mmol/L
  • Use EEG monitoring if needed
  • Treat seizures & myoclonus with sedation and anticonvulsants
  • Consider empiric antibiotics if aspiration is suspected
Step 6

Family communication

  • Provide clear & realistic updates
  • Explain clinical status and potential outcomes

Last reviewed · May 2026

MOC