Gastro medications

Antiemetics

GenericBrandRouteDoseNotes
OndansetronZofran, DansetPO / IV4–8 mg up to TDSQT caution; max 16 mg/day IV
MetoclopramidePrimperanPO / IV10 mg TDSProkinetic; max 5 days; EPS risk (avoid in young / Parkinson’s); renally cleared, adjust to CrCl
DomperidoneMotiliumPO10 mg TDSQT caution
CyclizineValoidPO / IV / IM50 mg TDSVestibular / mechanical nausea
ProchlorperazineStemetilPO / IM5 mg PO / 12.5 mg IMVertigo-associated nausea
PromethazinePhenerganPO / IM25 mgSedating
HaloperidolHaldolPO / IV / SC0.5–2 mgRefractory / palliative; QT

Laxatives & bowel regimen

GenericBrandRouteDoseNotes
LactuloseDuphalacPO15–30 mL OD–BDOsmotic; titrate to effect
Macrogol / PEGMovicol, ForlaxPO1 sachet OD–TDSOsmotic
BisacodylDulcolaxPO / PR5–10 mg PO / 10 mg PRStimulant
Glycerin suppositoryPR1 PRNRectal
Phosphate enemaFleetPR1 PRNRescue; caution in renal impairment

Proton pump inhibitors

GenericBrandRouteDose (PO)Dose (IV)Renal adjust
OmeprazoleLosec, MinisecPO / IV20–40 mg OD40 mg IV ODNo
PantoprazoleProtonPO / IV40 mg OD40 mg IV ODNo
EsomeprazoleNexiumPO / IV20–40 mg OD40 mg IV ODNo
DexlansoprazoleDexilantPO only30–60 mg ODNo

Avoid unnecessary PPI use in low-risk inpatients. IV PPI is not needed if the patient is tolerating PO.

Educational reference for clinicians. Doses are typical adult starting points — cross-check current local policy, the formulary, and renal/hepatic function before prescribing. Last reviewed: July 2026.

Last reviewed · July 2026

MOC